Background:
To preserve or improve the dimension and contour of the ridge following tooth extraction, deproteinized bovine bone mineral has been widely used to graft extraction socket and the procedure has been suggested to facilitate bone formation in extraction sockets and minimize loss of bone height and width.
Aim/Hypothesis:
The aim of the present study was to evaluate the bone regeneration capacity of synthetic peptide-coated bone bovine (Ossgen-X15®) compared to the non-modified deproteinized bovine bone in the extraction socket of maxillary teeth.
Material and Methods:
20 Maxillary teeth were scheduled for extraction as a consequence of advanced periodontitis in each subject. Of these, teeth with at least buccal or palatal wall remaining were selected. At the time of surgery, the distance from the midpoint of the extraction site perpendicular to the line connecting the occlusal surfaces of adjacent teeth was recorded at the most occlusally situated point both buccally and palatally. In addition, the depth of the extraction socket and the bucco-palatal width were also recorded.. After measuring, graft particles(Experimental group: Ossgen-X15® Control group: Bio-Oss®) were filled and packed and resorbable collagen membrane(Bio-Gide®) was placed to cover the marginal portion of the alveolar socket wall. Primary soft tissue closure was conducted via periosteal releasing incision on buccal flap. After 6 months follow-up, periapical radiograph was taken to identify the ossification of the socket. Three efficacy parameters were selected to compare the dimensional change between the two groups. The three parameters being the average height of alveolar walls - the mean depth of buccal and palatal walls - depth, and width. In patients who underwent implant treatments, bone biopsy was performed.
Results:
In the aspects of clinical parameters, the average change in the height of bony wall was +1.25±2.04mm in the experimental group and +1.20±2.01mm in the control group, and the depth change was +7.30±3.74mm in the experimental group and +7.10±3.07mm in the control group. The average change in widths was -1.30±1.33mm in the experimental group and -1.40±1.07mm in the control group, and when the values were converted, the percentage of width reduction was -13.15±12.92% in the experimental group and -15.19±10.87% in the control group Histologically, the two groups seemed to show a slight difference in composition of newly formed bone
Conclusions and clinical implications:
Peptide-coated bone mineral, used in the present study, is an effective bone substitute with the potential to enhance bone regeneration in the preservation of extraction sockets.
Background:
To preserve or improve the dimension and contour of the ridge following tooth extraction, deproteinized bovine bone mineral has been widely used to graft extraction socket and the procedure has been suggested to facilitate bone formation in extraction sockets and minimize loss of bone height and width.
Aim/Hypothesis:
The aim of the present study was to evaluate the bone regeneration capacity of synthetic peptide-coated bone bovine (Ossgen-X15®) compared to the non-modified deproteinized bovine bone in the extraction socket of maxillary teeth.
Material and Methods:
20 Maxillary teeth were scheduled for extraction as a consequence of advanced periodontitis in each subject. Of these, teeth with at least buccal or palatal wall remaining were selected. At the time of surgery, the distance from the midpoint of the extraction site perpendicular to the line connecting the occlusal surfaces of adjacent teeth was recorded at the most occlusally situated point both buccally and palatally. In addition, the depth of the extraction socket and the bucco-palatal width were also recorded.. After measuring, graft particles(Experimental group: Ossgen-X15® Control group: Bio-Oss®) were filled and packed and resorbable collagen membrane(Bio-Gide®) was placed to cover the marginal portion of the alveolar socket wall. Primary soft tissue closure was conducted via periosteal releasing incision on buccal flap. After 6 months follow-up, periapical radiograph was taken to identify the ossification of the socket. Three efficacy parameters were selected to compare the dimensional change between the two groups. The three parameters being the average height of alveolar walls - the mean depth of buccal and palatal walls - depth, and width. In patients who underwent implant treatments, bone biopsy was performed.
Results:
In the aspects of clinical parameters, the average change in the height of bony wall was +1.25±2.04mm in the experimental group and +1.20±2.01mm in the control group, and the depth change was +7.30±3.74mm in the experimental group and +7.10±3.07mm in the control group. The average change in widths was -1.30±1.33mm in the experimental group and -1.40±1.07mm in the control group, and when the values were converted, the percentage of width reduction was -13.15±12.92% in the experimental group and -15.19±10.87% in the control group Histologically, the two groups seemed to show a slight difference in composition of newly formed bone
Conclusions and clinical implications:
Peptide-coated bone mineral, used in the present study, is an effective bone substitute with the potential to enhance bone regeneration in the preservation of extraction sockets.
Background:
To preserve or improve the dimension and contour of the ridge following tooth extraction, deproteinized bovine bone mineral has been widely used to graft extraction socket and the procedure has been suggested to facilitate bone formation in extraction sockets and minimize loss of bone height and width.
Aim/Hypothesis:
The aim of the present study was to evaluate the bone regeneration capacity of synthetic peptide-coated bone bovine (Ossgen-X15®) compared to the non-modified deproteinized bovine bone in the extraction socket of maxillary teeth.
Material and Methods:
20 Maxillary teeth were scheduled for extraction as a consequence of advanced periodontitis in each subject. Of these, teeth with at least buccal or palatal wall remaining were selected. At the time of surgery, the distance from the midpoint of the extraction site perpendicular to the line connecting the occlusal surfaces of adjacent teeth was recorded at the most occlusally situated point both buccally and palatally. In addition, the depth of the extraction socket and the bucco-palatal width were also recorded.. After measuring, graft particles(Experimental group: Ossgen-X15® Control group: Bio-Oss®) were filled and packed and resorbable collagen membrane(Bio-Gide®) was placed to cover the marginal portion of the alveolar socket wall. Primary soft tissue closure was conducted via periosteal releasing incision on buccal flap. After 6 months follow-up, periapical radiograph was taken to identify the ossification of the socket. Three efficacy parameters were selected to compare the dimensional change between the two groups. The three parameters being the average height of alveolar walls - the mean depth of buccal and palatal walls - depth, and width. In patients who underwent implant treatments, bone biopsy was performed.
Results:
In the aspects of clinical parameters, the average change in the height of bony wall was +1.25±2.04mm in the experimental group and +1.20±2.01mm in the control group, and the depth change was +7.30±3.74mm in the experimental group and +7.10±3.07mm in the control group. The average change in widths was -1.30±1.33mm in the experimental group and -1.40±1.07mm in the control group, and when the values were converted, the percentage of width reduction was -13.15±12.92% in the experimental group and -15.19±10.87% in the control group Histologically, the two groups seemed to show a slight difference in composition of newly formed bone
Conclusions and clinical implications:
Peptide-coated bone mineral, used in the present study, is an effective bone substitute with the potential to enhance bone regeneration in the preservation of extraction sockets.
Background:
To preserve or improve the dimension and contour of the ridge following tooth extraction, deproteinized bovine bone mineral has been widely used to graft extraction socket and the procedure has been suggested to facilitate bone formation in extraction sockets and minimize loss of bone height and width.
Aim/Hypothesis:
The aim of the present study was to evaluate the bone regeneration capacity of synthetic peptide-coated bone bovine (Ossgen-X15®) compared to the non-modified deproteinized bovine bone in the extraction socket of maxillary teeth.
Material and Methods:
20 Maxillary teeth were scheduled for extraction as a consequence of advanced periodontitis in each subject. Of these, teeth with at least buccal or palatal wall remaining were selected. At the time of surgery, the distance from the midpoint of the extraction site perpendicular to the line connecting the occlusal surfaces of adjacent teeth was recorded at the most occlusally situated point both buccally and palatally. In addition, the depth of the extraction socket and the bucco-palatal width were also recorded.. After measuring, graft particles(Experimental group: Ossgen-X15® Control group: Bio-Oss®) were filled and packed and resorbable collagen membrane(Bio-Gide®) was placed to cover the marginal portion of the alveolar socket wall. Primary soft tissue closure was conducted via periosteal releasing incision on buccal flap. After 6 months follow-up, periapical radiograph was taken to identify the ossification of the socket. Three efficacy parameters were selected to compare the dimensional change between the two groups. The three parameters being the average height of alveolar walls - the mean depth of buccal and palatal walls - depth, and width. In patients who underwent implant treatments, bone biopsy was performed.
Results:
In the aspects of clinical parameters, the average change in the height of bony wall was +1.25±2.04mm in the experimental group and +1.20±2.01mm in the control group, and the depth change was +7.30±3.74mm in the experimental group and +7.10±3.07mm in the control group. The average change in widths was -1.30±1.33mm in the experimental group and -1.40±1.07mm in the control group, and when the values were converted, the percentage of width reduction was -13.15±12.92% in the experimental group and -15.19±10.87% in the control group Histologically, the two groups seemed to show a slight difference in composition of newly formed bone
Conclusions and clinical implications:
Peptide-coated bone mineral, used in the present study, is an effective bone substitute with the potential to enhance bone regeneration in the preservation of extraction sockets.