Background
Arterial hypertension is a frequent medical condition which affects more than 65% of the population over 60 years old, and more than half of them are receiving antihypertensive drugs, being most of them beta-blockers drugs. In addition, this patients are more likely to be treated with osseointegrated implants. Previous studies in traumatology and rheumatology have demonstrated that antihypertensive drugs have positive effects on bone metabolism.
Aims
The aim of this study is to evaluate the influence of these drugs in patients treated with osseointegrated implants.
Methods
A literature review was conducted in Pubmed and Science-Direct Databases over articles published within the last ten years with the keywords 'beta-blockers' AND 'antihypertensive drugs' AND 'osseointegrated dental implants' AND 'implant treatment'. All articles related with beta-blockers and dentistry were selected to carry out the review.
Results
Up to date, there are only four studies about this topic. The results of this studies suggest that betablockers drugs have a positive impact on bone metabolism and, consequently, on implant success rate. This happens through different pathways such as inhibition of osteoclast activity, stimulation of osteblastic cells and inhibition of renal calcium excretion.
Conclusions
The preliminary results show that beta-blockers drugs increase the medium and long-term success rate of the treatment with osseointegrated implants because of their protective role on bone metabolism. Nevertheless, further randomized clinical trials in humans are necessary to confirm the advantages of this drugs and to evaluate the long terms effects.
Background
Arterial hypertension is a frequent medical condition which affects more than 65% of the population over 60 years old, and more than half of them are receiving antihypertensive drugs, being most of them beta-blockers drugs. In addition, this patients are more likely to be treated with osseointegrated implants. Previous studies in traumatology and rheumatology have demonstrated that antihypertensive drugs have positive effects on bone metabolism.
Aims
The aim of this study is to evaluate the influence of these drugs in patients treated with osseointegrated implants.
Methods
A literature review was conducted in Pubmed and Science-Direct Databases over articles published within the last ten years with the keywords 'beta-blockers' AND 'antihypertensive drugs' AND 'osseointegrated dental implants' AND 'implant treatment'. All articles related with beta-blockers and dentistry were selected to carry out the review.
Results
Up to date, there are only four studies about this topic. The results of this studies suggest that betablockers drugs have a positive impact on bone metabolism and, consequently, on implant success rate. This happens through different pathways such as inhibition of osteoclast activity, stimulation of osteblastic cells and inhibition of renal calcium excretion.
Conclusions
The preliminary results show that beta-blockers drugs increase the medium and long-term success rate of the treatment with osseointegrated implants because of their protective role on bone metabolism. Nevertheless, further randomized clinical trials in humans are necessary to confirm the advantages of this drugs and to evaluate the long terms effects.