Background
Peri-implantitis (PI) is a prevalent infectious disease without a consensual surgical treatment. Leucocyte plasma rich fibrin (L-PRF) is associated with less postoperative pain with positive and promising results on periodontology, bone regeneration, osseointegration and peri-implantitis, proven by a recent clinical study.
Aims
The aim of this study is to present a clinical report about a regenerative approach for the treatment of peri-implantitis with L-PRF.
Methods
This clinical report has two clinical cases. Case 1: male, healthy, non-smoker, no periodontits. Implant 14 (4,3x10mm) with 7 years in function. Baseline: deepest probing depth (PD)=9mm, bleeding-on-probing. Case 2: male, healthy, non-smoker no periodontitis. Implants 36 and 37 (both 4,3x10mm) with 4 years in function. Baseline: deepest PD=8mm (#36) and 6mm (#37), bleeding-on-probing. Radiographs were taken at baseline and both cases presented radiographic bone loss. L-PRF membranes were prepared according to Choukroun´s protocol. After full thickness flap granulation tissue was removed and implant surface decontaminated with air-flow + glycine powder and saline irrigation. Peri-implant defects had operative circumferential and supra-bony components and were filled with compacted L-PRF membranes. Additional membranes covered the implants and flaps were sutured with a polypropylene 5-0 internal mattress suture.
Results
The patient’s blood collection is a simple procedure that allowed the acquisition of a considerable amount of L-PRF membranes. These membranes were easy to handle, with a firm consistence and did not dilacerate when pressured in the peri-implant defect. Their consistence allowed a clear dissection according to the anatomy of the peri-implant defect. On both cases the immediate post-surgical (7, 15 and 30 days) control was associated with no swelling nor pain. Resolution of peri-implantitis lesions were achieved after 6 months follow-up.
Conclusions
The evidence level of this technique on peri-implantits is very low, with only one study using L-PRF on peri-implantitis surgery whose results suggests his potential to enhance wound healing and implants reosseointegration. L-PFR membrane contains platelets, leukocytes, cytokines and stem cells. Is low cost, easy to obtain/handle, associated with no post-surgical pain/edema. These preliminary results are promising, nevertheless more robust controlled trials are needed for further evaluation.
Background
Peri-implantitis (PI) is a prevalent infectious disease without a consensual surgical treatment. Leucocyte plasma rich fibrin (L-PRF) is associated with less postoperative pain with positive and promising results on periodontology, bone regeneration, osseointegration and peri-implantitis, proven by a recent clinical study.
Aims
The aim of this study is to present a clinical report about a regenerative approach for the treatment of peri-implantitis with L-PRF.
Methods
This clinical report has two clinical cases. Case 1: male, healthy, non-smoker, no periodontits. Implant 14 (4,3x10mm) with 7 years in function. Baseline: deepest probing depth (PD)=9mm, bleeding-on-probing. Case 2: male, healthy, non-smoker no periodontitis. Implants 36 and 37 (both 4,3x10mm) with 4 years in function. Baseline: deepest PD=8mm (#36) and 6mm (#37), bleeding-on-probing. Radiographs were taken at baseline and both cases presented radiographic bone loss. L-PRF membranes were prepared according to Choukroun´s protocol. After full thickness flap granulation tissue was removed and implant surface decontaminated with air-flow + glycine powder and saline irrigation. Peri-implant defects had operative circumferential and supra-bony components and were filled with compacted L-PRF membranes. Additional membranes covered the implants and flaps were sutured with a polypropylene 5-0 internal mattress suture.
Results
The patient’s blood collection is a simple procedure that allowed the acquisition of a considerable amount of L-PRF membranes. These membranes were easy to handle, with a firm consistence and did not dilacerate when pressured in the peri-implant defect. Their consistence allowed a clear dissection according to the anatomy of the peri-implant defect. On both cases the immediate post-surgical (7, 15 and 30 days) control was associated with no swelling nor pain. Resolution of peri-implantitis lesions were achieved after 6 months follow-up.
Conclusions
The evidence level of this technique on peri-implantits is very low, with only one study using L-PRF on peri-implantitis surgery whose results suggests his potential to enhance wound healing and implants reosseointegration. L-PFR membrane contains platelets, leukocytes, cytokines and stem cells. Is low cost, easy to obtain/handle, associated with no post-surgical pain/edema. These preliminary results are promising, nevertheless more robust controlled trials are needed for further evaluation.