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Abstract
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Congenitally missing teeth (CMT), comprehensively describing the developmental failure of teeth, is one of the most common dental anomalies. Despite using various definitions, literature has been mainly focusing on prevalence, while lacking in-depth information on patterns of patients with CMT.**The present study aimed to explore, describe and evaluate disparities within a CMT-cohort especially regarding sex-dimorphism, occurrence, severity (hypodontia oligodontia) and patterns of CMT.** Outcome Measures**• Patient demographics- date-of-birth-year, gender (female male)**• Number of CMT per patient**• CMT-severity-groups**o hypodontia (1-6 CMT)**• mild (1-2 CMT), moderate (3-5 CMT) **o oligodontia (6-28 CMT)**• intense (6-9 CMT), severe (10-14 CMT), extreme (15-28 CMT) **• CMT-affected tooth- incisor, canine, premolar, molar **• CMT-region and symmetry**o quadrant **o left right**o maxillary mandibular**o unilateral bilateral**o anterior=incisors + canines middle=premolars posterior=molars**• Growth-type- horizontal, normal, vertical **• Medical-history- underlying diseases, other dental anomalies, impacted tooth.**• Family-history- The consanguinity, if documented, was itemized according to their shared average DNA **The TAC was the tool to determine the patterns of CMT of a non-syndromic population of all fields of dental departments with a minimum age of 10 years.**Not finished, still in process**The first results are presented here-****The average CMT-number per patient was 5.5 (group1, n=816, 59.9% female), 6.3 (group2, n=34, 44.1% female), and 15.1 (group3, n=27, 29.6% female). There were significantly more patients with oligodontia in group3 (77.8%) than in group1 (28.6%, P<0.001) and group2 (44.1%, P=0.010). Findings regarding group1 were that the most frequent CMT was the 2nd premolar+ there were no significant differences between the right and left side, whereas more CMT affected the maxilla+ the majority of patients presented with bilateral-CMT (82.8%)+ the CMT-number was higher in females, but more males had severer forms+ certain CMT-types differed by gender+ the horizontal growth-type was predominant, but it was not associated with CMT-regions+ and CMT was related to first-grade-relatives.Non-syndromic CMT-patients (<9years of age) revealed gender-specific association regarding CMT-numbers, severity groups, and certain CMT-affected teeth. Certain pattern were observed regarding severity-group and gender. The premolars were predominant regarding CMT-affected tooth, bilateral-CMT, and CMT-region.**
Congenitally missing teeth (CMT), comprehensively describing the developmental failure of teeth, is one of the most common dental anomalies. Despite using various definitions, literature has been mainly focusing on prevalence, while lacking in-depth information on patterns of patients with CMT.**The present study aimed to explore, describe and evaluate disparities within a CMT-cohort especially regarding sex-dimorphism, occurrence, severity (hypodontia oligodontia) and patterns of CMT.** Outcome Measures**• Patient demographics- date-of-birth-year, gender (female male)**• Number of CMT per patient**• CMT-severity-groups**o hypodontia (1-6 CMT)**• mild (1-2 CMT), moderate (3-5 CMT) **o oligodontia (6-28 CMT)**• intense (6-9 CMT), severe (10-14 CMT), extreme (15-28 CMT) **• CMT-affected tooth- incisor, canine, premolar, molar **• CMT-region and symmetry**o quadrant **o left right**o maxillary mandibular**o unilateral bilateral**o anterior=incisors + canines middle=premolars posterior=molars**• Growth-type- horizontal, normal, vertical **• Medical-history- underlying diseases, other dental anomalies, impacted tooth.**• Family-history- The consanguinity, if documented, was itemized according to their shared average DNA **The TAC was the tool to determine the patterns of CMT of a non-syndromic population of all fields of dental departments with a minimum age of 10 years.**Not finished, still in process**The first results are presented here-****The average CMT-number per patient was 5.5 (group1, n=816, 59.9% female), 6.3 (group2, n=34, 44.1% female), and 15.1 (group3, n=27, 29.6% female). There were significantly more patients with oligodontia in group3 (77.8%) than in group1 (28.6%, P<0.001) and group2 (44.1%, P=0.010). Findings regarding group1 were that the most frequent CMT was the 2nd premolar+ there were no significant differences between the right and left side, whereas more CMT affected the maxilla+ the majority of patients presented with bilateral-CMT (82.8%)+ the CMT-number was higher in females, but more males had severer forms+ certain CMT-types differed by gender+ the horizontal growth-type was predominant, but it was not associated with CMT-regions+ and CMT was related to first-grade-relatives.Non-syndromic CMT-patients (<9years of age) revealed gender-specific association regarding CMT-numbers, severity groups, and certain CMT-affected teeth. Certain pattern were observed regarding severity-group and gender. The premolars were predominant regarding CMT-affected tooth, bilateral-CMT, and CMT-region.**
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